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Specific alleles at immune genes, rather than genome-wide heterozygosity, are related to immunity and survival in the critically endangered Attwater's prairie-chicken
The negative effects of inbreeding on fitness are serious concerns for populations of endangered species. Reduced fitness has been associated with lower genome-wide heterozygosity and immune gene dive
DataONE2020-06-24 更新50
Trans-Species Polymorphism and Selection in the MHC Class II DRA Genes of Domestic Sheep
Highly polymorphic genes with central roles in lymphocyte mediated immune surveillance are grouped together in the major histocompatibility complex (MHC) in higher vertebrates. Generally, across verte
NIAID Data Ecosystem30
Table 1_Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations.xlsx
IntroductionPsoriasis and chronic mucocutaneous candidiasis (CMC), although distinct in their clinical manifestations, often coexist within specific patient cohorts. Despite this intriguing clinical o
NIAID Data Ecosystem20
The association between HLA-DRB1 alleles and antibody response to individual antigens.
The association between HLA-DRB1 alleles and antibody response to individual antigens.
NIAID Data Ecosystem30
MHC allele numbers.
Kruskal-Wallis test for equal medians and following Dunn’s posthoc test. Dunn’s z values above the diagonal, Bonferroni corrected p-values below the diagonal. Significant p-values are marked in bold t
NIAID Data Ecosystem20
