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Role and function of Sox4 in BCR-ABL1 driven pre-B cells. Mus musculus

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NIAID Data Ecosystem2026-03-07 收录
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In order to investigate the function of Sox4 in ALL, we isolated bone marrow cells from Sox4 fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-ERT2 or empty vector control (ERT2) and subjected to gene expression analysis. Overall design: 24h after induction of deletion with 4OHT, total RNA of cells was extracted and subjected to gene expression analysis.

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2012-03-15
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