Melanomas tend to become less pigmented in the course of malignant progression. Thus, as proliferation increases, the tumors are decreasingly characterized by the tissue-specific phenotype of normally
GEE analysis methods and Tables S1–S3. File S1 shows detailed methods of generalized estimating equation (GEE) analysis, correlation between TRECs and naive T cell percentages (Table S1), regression a
Immune checkpoint blockade (ICB) is standard-of-care for patients with metastatic melanoma. It may re-invigorate T cells recognizing tumors, and several tumor antigens have been identified as potentia
Transcriptomic profile of Creld1 deficient naïve CD4+ T cells and control 1-year-old mice. Sorted naïve CD4+ T cells were analysed to underling the transcriptomic impact Creld1 deficiency in the aging
