Extrathyroidal extension (ETE) affects papillary thyroid cancer (PTC) prognosis. The objective of this study was to identify biomarkers for ETE and explore the mechanisms controlling its development i
To evaluate SASP in an in vitro model, we analyzed the gene expression profile of BRAFV600E-induced OIS thyrocytes by RNA sequencing and detected an increase in SASP expression. Overall design: Exami
Growth differentiation factor 15(GDF15)displays aberrant expression in multiple malignancies, yet its role and underlying mechanisms in thyroid carcinoma remain unclear. This study aimed to investigat
We tried to analyze the effect of FTO on papillary thyroid carcinoma. We constructed a FTO overexpression stable cell line of papillary thyroid carcinoma cells. We performed meRIP-seq sequencing analy
Multiple lines of evidence have highlighted that long noncoding RNAs (lncRNAs) serve as a novel class of regulators of cancer biological processes. Currently, our knowledge of lncRNAs in papillary thy