The androgen receptor (AR) is a key driver of prostate cancer (PC), even in the state of castration-resistant PC (CRPC), and frequently even after treatment with second-line hormonal therapies such as

NIAID Data Ecosystem10

RNA-seq in RWPE1 with inducible expression of MACC constructs.. RNA-seq in RWPE1 with inducible expression of MACC constructs.

癌症转录调控

激素受体信号通路

The androgen receptor (AR) is the central determinant of prostate tissue identity and differentiation, controlling normal, growth-suppressive prostate-specific gene expression. It is also a key driver

NIAID Data Ecosystem00

ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [Bulk RNA-seq]

前列腺癌分子机制

激素受体信号通路

We report the effects of ERG on prostate tumorigenesis, ERG-mediated oncogene addiction, and downstream AR signaling pathways. We determined that ERG facilitates AR-signaling and mediates transformati

NIAID Data Ecosystem40

Primer sequences used in qPCR.

乳腺细胞分子机制

qPCR基因表达分析

It has been established that essential amino acids (EAA) regulate protein synthesis in mammary epithelial cells by rapidly altering the phosphorylation state of translation factors. However, the long-

Figshare2024-12-20 更新10

Time-course effect of estradiol and ERa17p on Early Gene expression in SKBR3 cells

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