Structure of AKT2 with compound 3

Structure of AKT2 with compound 3 Descriptor: 1,2-ETHANEDIOL, 4-{2-[({4-[(2P)-2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl}methyl)amino]ethyl}-2-hydroxybenzaldehyde, RAC-beta serine/threonine-protein kinase Authors: Craven, G.B, Ma, X, Taunton, J. Deposit date: 2024-05-29 Release date: 2024-09-04 Last modified: 2025-01-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Mutant-selective AKT inhibition through lysine targeting and neo-zinc chelation. Nature, 637, 2025