C9orf72 ubiquitin and interaction proteomics
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
C9orf72 binds SMCR8 to from a robust complex that regulates small GTPases, lysosomal integrity and autophagy. In contrast to this functional understanding, we know far less about assembly and turnover of the C9orf72-SMCR8 complex. Loss of either subunit causes the concurrent ablation of the respective partner. However, the molecular mechanism underlying this interdependence remains elusive.
创建时间：
2023-05-10
