AVIDa-hIL6
收藏OpenML2025-02-18 更新2025-12-20 收录
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资源简介：
AVIDa-hIL6 is an antigen-variable domain of heavy chain of heavy chain antibody (VHH)
interaction dataset produced from an alpaca immunized with the human interleukin-6 (IL-6)
protein. By leveraging the simple structure of VHHs, which facilitates identification of
full-length amino acid sequences by DNA sequencing technology, AVIDa-hIL6 contains 573,891
antigen-VHH pairs with amino acid sequences. All the antigen-VHH pairs have reliable
labels for binding or non-binding, as generated by a novel labeling method. Furthermore,
AVIDa-hIL6 has the wild type and 30 mutants of the IL-6 protein as antigens, and it
includes many sensitive cases in which point mutations in IL-6 enhance or inhibit antibody
binding. We envision that AVIDa-hIL6 will serve as a valuable benchmark for machine
learning research in the growing field of predicting antigen-antibody interactions.
创建时间：
2025-02-18
