Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione
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Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione Descriptor: (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... Authors: Liu, Y.L, Oldfield, E. Deposit date: 2014-02-23 Release date: 2014-07-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site. Proc.Natl.Acad.Sci.USA, 111, 2014
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2014-02-23
