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Genome-wide distribution of off-target effects determined by Detect-seq and unbiased sgRNA-target pair library analysis of indicated CBEs
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2022-05-06
相关数据集
Additional file 5: Table S2. of An efficient system for homology-dependent targeted gene integration in medaka (Oryzias latipes)
The numbers of potential off-target sequences in reference genomes of teleost fish species. Numbers of genomic sites with up to 3Â bp mismatches in the total 21Â bp sequences are shown. (XLSX 11 kb)
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Transduction_of_NIH3T3_with_BE3_and_with_sgRNA_vectors_WGS_. Transduction_of_NIH3T3_with_BE3_and_with_sgRNA_vectors_WGS_
Recent reports document that cytidine base editors (CBEs) can induce substantial, genome wide, guide-dependent and independent off-target base modifications (Xin et al., Signal Transduction and Target
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Cytosine base editing systems with minimized off-target effect and molecular size
The sequence data were generated in order to evaluate the performance of CBE (cytosine base editor) variants Target-AID2S,3S in comparison with CBE variants Target-AID, YE1, YE2, and R33A+K34A.
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CaS1OT8_F1Sanger Sequencing results for the off-targets and CASR gene in F1 and F2 generation
Sanger sequencing results from the off-target analysis CaS1OT8_F1
Figshare2023-07-21 更新30
Cas9 interactions with host RNAs and transposable elements impair neurodevelopment (RNA-seq). Cas9 interactions with host RNAs and transposable elements impair neurodevelopment (RNA-seq)
The CRISPR (clustered regulatory interspaced short palindromic repeats)/ Cas9 (CRISPR-associated protein 9) system-based precise genome editing has revolutionized biomedical studies. As the CRISPR/Cas
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