官方服务：
资源简介：
Analysis of a conditional knockout of Fbxo7/Park15 expression in mouse brains.
应用场景：
创建时间：
2019-08-28
相关数据集
a-Synuclein Translocates To The Nucleus To Activate Retinoic Acid- Dependent Gene Transcription
a-Synuclein (a-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). It is primarily cytosolic and reversibly interacts with cell membranes. a-Syn also occurs in the nucleus, h
NIAID Data Ecosystem90
Next generation sequencing reveals upregulation of the lncRNA LINC-PINT in the substantia nigra of human Parkinson's disease patients compared to control donors
Parkinson's disease (PD) is the second most common neurodegenerative disease, involving the selecive death of dopaminergic neurons in the substantia nigra pars compacta brain region. Here, we performe
NIAID Data Ecosystem60
GPNMB confers risk for Parkinson’s disease through interaction with alpha-synuclein
Many risk loci for Parkinson’s disease (PD) have been identified by genome-wide association studies (GWAS), but target genes and mechanisms remain largely unknown. We linked the GWAS-derived chromosom
NIAID Data Ecosystem50
Additional file 5 of Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition
Additional file 5. ErmineR pathway enrichment analyses before and after accounting for cell composition.
Figshare2020-04-22 更新70
Identification of salsolinol as an RNA m6A methylation inducer that mediates dopaminergic neuronal death by regulating YAP1 and autophagy
Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Sal) is a catechol isoquinoline that can cause neurotoxicity because of its structural similarity with MPTP (1-methyl-4-phenyl-1,2,3,
Alliance of Genome Resources60
