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Comparative IC50 for antimonial against in vivo recovered promastigotes.

NIAID Data Ecosystem2026-03-10 收录

数据链接：

https://figshare.com/articles/dataset/Comparative_IC_sub_50_sub_for_antimonial_against_i_in_vivo_i_recovered_promastigotes_/7430588 数据链接链接失效反馈

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资源简介：

Comparative IC50 for antimonial against in vivo recovered promastigotes.

应用场景：

创建时间：

2018-12-06

利什曼病药物筛选

高内涵成像分析

Leishmaniasis is a tropical disease threatening 350 million people from endemic regions. The available drugs for treatment are inadequate, with limitations such as serious side effects, parasite resis

Figshare2016-01-19 更新40

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays

利什曼病药物筛选

高通量药物发现模型

The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an estimated 1 million new cases each year. Current treatments are toxic, expensive, difficult to admi

NIAID Data Ecosystem30

Drug sensitivity of wild, CYP710C1 OE and CYP710C1/NEO promastigotes.

利什曼病药物筛选

药物敏感性

Values were determined in promastigotes of wild-type, CYP710C1 OE and CYP710C1/NEO of L. donovani after 72 h of drug addition. IC50 are given as mean ± S.D of at least two independent determinations w

NIAID Data Ecosystem20

Half maximal effective concentration (EC 50 ) of raloxifene against Leishmania spp.

利什曼病药物筛选

寄生虫药效评估

aParasite form: P: promastigotes; LA: lesion derived amastigotes; IA: intracelullar amastigotes. Half maximal effective concentration against promastigotes and axenic lesion-derived amastigotes was de

NIAID Data Ecosystem30

Inhibitory concentrations of Immucillins and Glucantime against intracellular amastigotes of L . (L . ) infantum chagasi and citotoxicity to macrophages.

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细胞毒性评估

CC50 and EC50 were determined by linear interpolation after addition of the drugs at 0 h (10 μM, 500 μM and 5mM for IC50) and (0.5 μM, 5 μM and 10 μM for EC5 Inhibitory concentrations of Immucillins a

NIAID Data Ecosystem30

Comparative IC<sub>50</sub> for antimonial against <i>in vivo</i> recovered promastigotes.

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