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Cryo-EM structure of the human Sec61 complex inhibited by cyclotriazadisulfonamide (CADA)

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Protein Data Bank Japan2023-09-06 更新2026-05-23 收录
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Cryo-EM structure of the human Sec61 complex inhibited by cyclotriazadisulfonamide (CADA) Descriptor: 9-benzyl-1,5-bis(4-methylbenzene-1-sulfonyl)-3-methylidene-1,5,9-triazacyclododecane, Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, ... Authors: Park, E, Itskanov, S. Deposit date: 2022-07-12 Release date: 2023-05-24 Last modified: 2023-09-06 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: A common mechanism of Sec61 translocon inhibition by small molecules. Nat.Chem.Biol., 19, 2023

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2022-07-12
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