Inhibitor of MDM2-p53 Interaction
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Inhibitor of MDM2-p53 Interaction Descriptor: 1-[[(1~{R})-2-[(5-chloranylpyridin-2-yl)methyl]-1-(4-chlorophenyl)-7-fluoranyl-3-oxidanylidene-5-(2-oxidanylpropan-2-yl)isoindol-1-yl]oxymethyl]cyclopropane-1-carboxamide, E3 ubiquitin-protein ligase Mdm2, SULFATE ION Authors: Williams, P.A. Deposit date: 2021-01-13 Release date: 2021-04-07 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction. J.Med.Chem., 64, 2021
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2021-01-13
