Here, x ± y stands for the value of optimized parameter x with standard deviation y. The standard deviation is evaluated using the data of 103 independent SA simulations. Parameter values tabulated in
aMinimal and Maximal values that support first order Min oscillations in the fully labelled system at 3.5 μm. bCalculated from experimental measurements on GFP-labelled fusion proteins. Rate Parameter
(A) Values used for the PU.1–GATA-1 network in Equation 3. (B) Values of the additional parameters used for the PU.1–GATA-1 network including the gene X in Equation 4. For Figure 2A, , and for Figure