Integration sites of HIV in Homo sapiens HEK293 cells; raw sequence reads. Homo sapiens

NIAID Data Ecosystem2026-03-09 收录

HIV整合位点

基因组整合偏好性

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA295930 数据链接链接失效反馈

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资源简介：

Genome-wide analysis of 1 million HIV integration site to study HIV integration preference.

创建时间：

2015-09-17

Integration sites sequencing of HIV infection on ZNF417 ZNF587 dKO 293T cells. Integration sites sequencing of HIV infection on ZNF417 ZNF587 dKO 293T cells

HIV整合位点

基因组测序

We infected ZNF417 ZNF587 dKO 293T or control 293T with NL4.3 virus for 48 hours. Then genomic DNA was purified from cell lysis with by phenol chloroform. DNA was sheared into 300 bp-500 bp random fra

NIAID Data Ecosystem50

HIV-1 integration site landscape across compartments and cell subsets. Homo sapiens

HIV潜伏库定位

HIV整合位点

Assessment of HIV integration sites from acute, chronic, and ART-treated HIV-infected individuals at a tissue compartment and cell subset resolution. This will serve as a resource for researchers inte

NIAID Data Ecosystem40

We performed two independent infection on Jurkat T cells by barcoded HIV (2 biological replicates). Each sample preparation and data analysis was done in parallel in 2 replicates.. BHIVe sequencing data

HIV整合位点

病毒转录追踪

We propose a technology B-HIVE, which allows us to map HIV integrations in a cell population and measure their individual transcription. The principle of B-HIVE is to tag individual viral genomes with

NIAID Data Ecosystem30

The chromatin landscape at the HIV-1 provirus integration site determines viral expression

HIV整合位点

病毒表观遗传学

We investigated the link between HIV-1 integration by using B-HIVE and LEDGINs. B-HIVE tracks insert-specific HIV expression by tagging a unique barcode in the HIV genome. LEDGINs are antivirals that

NIAID Data Ecosystem40

HIV Integration site analysis from HIV-1-infected CD4+ clones specific to CMV and Gag antigens

HIV整合位点

病毒-宿主相互作用

Integration site analysis from HIV-1-infected CD4+ clones specific to CMV and Gag antigens

NIAID Data Ecosystem40