Structure of human SIRT2 in complex with 1,2,4-Oxadiazole inhibitor and ADP ribose.
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Structure of human SIRT2 in complex with 1,2,4-Oxadiazole inhibitor and ADP ribose. Descriptor: 1,2-ETHANEDIOL, 3-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]propan-1-ol, ACETATE ION, ... Authors: Moniot, S, Steegborn, C. Deposit date: 2016-11-04 Release date: 2017-03-15 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Development of 1,2,4-Oxadiazoles as Potent and Selective Inhibitors of the Human Deacetylase Sirtuin 2: Structure-Activity Relationship, X-ray Crystal Structure, and Anticancer Activity. J. Med. Chem., 60, 2017
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2016-11-04
