首页/数据集/Adeno-associated virus serotype 6 basic regions in complex with importin alpha 2

Adeno-associated virus serotype 6 basic regions in complex with importin alpha 2

NIAID Data Ecosystem2026-05-02 收录

腺相关病毒载体

核转运蛋白相互作用

数据链接：

https://www.rcsb.org/structure/9CFT 数据链接链接失效反馈

官方服务：

资源简介：

Adeno-associated virus serotype 6 basic regions in complex with importin alpha 2

应用场景：

创建时间：

2025-02-12

相关数据集

Figure5F_Nup54(0)_plusRan_plusKaps_t90

核孔复合物构象变化

核转运蛋白相互作用

Karyopherin content at the nuclear periphery induces conformational changes in Nup54-mEGFP494 but not Nup133-mEGFP.

NIAID Data Ecosystem70

Table_2_Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness.docx

耳聋基因治疗

腺相关病毒载体

Hearing impairment is the most common sensory disorder in humans. So far, rehabilitation of profoundly deaf subjects relies on direct stimulation of the auditory nerve through cochlear implants. Howev

NIAID Data Ecosystem40

Figure5B_Nup133(-9)_noRan_PlusKap_t00

核孔复合体

核转运蛋白相互作用

Karyopherin content at the nuclear periphery induces conformational changes in Nup54-mEGFP494 but not Nup133-mEGFP.

Figshare2020-12-07 更新10

AAV-genome population sequencing detects the repair of mutated ITR structures and the impact of guide RNA cassette designs on vector genome integrity. Adeno Associated Virus (AAV)

腺相关病毒载体

基因组完整性评估

Using AAV-Genome-Population sequencing (AAV-GPseq), we previously found that self-complementary AAV vector designs with strong DNA secondary structures can cause a high degree of truncation events, im

NIAID Data Ecosystem40

Data_Sheet_1_Accurate Quantification and Characterization of Adeno-Associated Viral Vectors.pdf

腺相关病毒载体

基因组质量控制

One of the main challenges in the gene therapy viral vector development is to establish an optimized process for its large scale production. This requires optimization for upstream and downstream proc

NIAID Data Ecosystem20