Iron is both, an essential compound for many metabolic processes, and iron deficiency can impact on the proliferation of cells including lymphocytes but also tumor cells. On the other hand, excess iro
Natural killer (NK) cells are crucial for immune defense against tumors, but their function is often impaired in the tumor microenvironment. High mobility group box 2 (HMGB2), a chromatin-associated p
Programming cell signaling during T-cell activation represents a simple strategy for improving the potency of therapeutic T-cell products. Stim-R⢠technology (Lyell Immunopharma) is a customizable,
Effective strategies to reinvigorate the immune system are needed to improve outcomes in small cell lung cancer (SCLC). Targeting Src family kinases with dasatinib (Dasa) can elicit immunomodulatory e