Crystal structure of human carbonic anhydrase II in complex with a benzenesulfonamide inhibitor
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Crystal structure of human carbonic anhydrase II in complex with a benzenesulfonamide inhibitor Descriptor: 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Avvaru, B.S, Wagner, J, Robbins, A.H, McKenna, R. Deposit date: 2010-05-21 Release date: 2011-03-09 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency. Chem.Commun.(Camb.), 46, 2010
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2010-05-21
