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ASB9 promotes ubiquitin-mediated degradation of TNP2 to facilitate histone-to-protamine transition in humans and mice

Name: ASB9 promotes ubiquitin-mediated degradation of TNP2 to facilitate histone-to-protamine transition in humans and mice
Creator: West China The Second Hospital
Published: 2025-11-19T20:06:01+08:00

integrated proteome resources2026-02-07 收录

精子发生

泛素介导的蛋白质降解

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0014324000 数据链接链接失效反馈

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资源简介：

ASB9 promotes ubiquitin-mediated degradation of TNP2 to facilitate histone-to-protamine transition in humans and mice

应用场景：

提供机构：

West China The Second Hospital

创建时间：

2025-11-19

精子发生

表观遗传

Gametogenetin binding protein 2 (GGNBP2) was indispensable in normal spermatids for transformation into mature spermatozoa in mice, and when Gametogenetin binding protein 2 is bound to BRCC36 and RAD5

DataCite Commons2024-08-07 更新100

RNA-binding protein complex AMG-1/SLRP-1 mediates germline development and spermatogenesis by maintaining mitochondrial homeostasis in Caenorhabditis elegans [LACE-seq]. RNA-binding protein complex AMG-1/SLRP-1 mediates germline development and spermatogenesis by maintaining mitochondrial homeostasis in Caenorhabditis elegans [LACE-seq]

线粒体遗传调控

精子发生

The mechanisms of RNA-binding proteins (RBPs)-mediated post-transcriptional regulation of pre-existing mRNAs, which is essential for spermatogenesis, remains poorly understood. Here, we identify a ger

NIAID Data Ecosystem50

Sperm_H3K4me3_replicate1.filtered.seq_depth_norm.bw

表观遗传学

精子发生

Sperm_H3K4me3_replicate1.filtered.seq_depth_norm.bw

Figshare2022-10-19 更新40

DataSheet_1_Changes in Expressions of Spermatogenic Marker Genes and Spermatogenic Cell Population Caused by Stress.xlsx

精子发生

压力影响

Many young adults are in a state of stress due to social and psychological pressures, which may result in male reproductive dysfunction. To provide new insight into this phenomenon, we investigated th

NIAID Data Ecosystem90

Identification and characterization of BEND2 as a novel and key regulator of meiosis during mouse spermatogenesis [RNA-Seq II]. Identification and characterization of BEND2 as a novel and key regulator of meiosis during mouse spermatogenesis [RNA-Seq II]

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基因表达调控

To describe the changes of transcriptome in Bend2 knockout mice, we conducted RNA-seq analyses by using spermatocytes from d12 (12-days after birth) Bend2 WT and KO mice. We found BEND2 contributed to

NIAID Data Ecosystem40

ASB9 promotes ubiquitin-mediated degradation of TNP2 to facilitate histone-to-protamine transition in humans and mice

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