trans-eQTL and aQTL results between BMI-adjusted T2D GWAS SNPs and HOMA-IR master regulators (MRs) with at least one significant QTL at the locus at FDR < 0.05.
Recent genome-wide association studies (GWAS) identified DUSP8, a dual-specificity phosphatase targeting MAP kinases, as type 2 diabetes (T2D) risk gene. Here, we unravel Dusp8 as gatekeeper in the hy
Elevated fasting blood glucose (FBG) has been associated with increased risk for development of type 2 diabetes. Single nucleotide polymorphisms (SNPs) in G6PC2 are the most important common determina
All identified sentinel cis eQTLs. List of possible causal variant cis eQTL based on location and lowest p value including CAGE-cluster and SNPs chromosomal positions; gene ID; biotype class according
RNA-seq-enabled Expression Quantitative Trait Locus (eQTL) in Populus. Hybrid plant was created by crossing P. trichocarpa (93-968) and P. deltoides (ILL-101), and the F1 hybrid (52-225) was then cros