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Transcriptional analysis of whole substantia nigra in Parkinson's disease
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2025-01-24
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NOS1AP is a novel molecular target and critical factor in TDP-43 pathology.
Effects of hnRNPD and hnRNPU silencing on gene expression in SH-SY5Y cells. SH-SY5Y cells were treated with siRNA anti-hnRNPD (n=3), or anti-hnRNPU (n=3), or anti-Luciferase (n=3)
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Additional file 4 of Single-nucleus RNA-seq identifies Huntington disease astrocyte states
Additional file 4. Supplementary Data. (1) Raw counts and RPKM counts of Bulk RNAseq data. (2)Results of differential gene expression analysis of each astrocytic cluster against all other clusters.
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Comprehensive Analysis of Gene Expression Patterns in Friedreich's Ataxia Fibroblasts by RNA Sequencing Reveals Altered Levels of Protein Synthesis Factors and Solute Carriers
Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disease usually caused by large homozygous expansions of GAA repeat sequences in intron 1 of the frataxin (FXN) gene. FRDA patie
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Cell type specific gene expression analysis in pre-symptomatic huntington's disease.
Selective neuronal vulnerability is a common, yet poorly understood characteristic of neurodegenerative diseases and is particularly prominent in Huntington's disease (HD). To determine how presence o
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Differentially expressed mRNA transcripts in the brains of aged Polg mutator mice as determined by RNA-seq.
1Log2 (Mutator/Control). 2P-value adjusted using Benjamini-Hochberg method to control the FDR.
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