Aromatic hydroxylation of pseudocumene and mesitylene with P450 BM3 yields key phenolic building blocks for a-tocopherol synthesis. Site-saturation mutagenesis generated a new P450 BM3 mutant, named “
Regio-divergent propargylic substitution to generate functionally diverse products from identical starting materials remains a formidable challenge, probably due to the unpredictable regiochemical com
Ni-Fe/SiO2 and Ni-Cu/SiO2 catalysts are promising candidates for CO2 hydrogenation towards value-added products. We aim to understand the influence of Fe and Cu on electronic and structural properties