Discovery of (E)-N1-(3-fluorophenyl)-N3-(3-(2-(pyridin-2-yl)vinyl)-1Hindazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)

Name: Discovery of (E)-N1-(3-fluorophenyl)-N3-(3-(2-(pyridin-2-yl)vinyl)-1Hindazol-6-yl)malonamide (CHMFL-KIT-033) as a Novel c-KIT T670I Mutant Selective Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs)
Creator: Wenchao Wang; 合肥物质科学研究院; Qingwang Liu; Zongru Jiang; Zhenquan Hu; Fengming Zou; Junjie Wang; Kailin Yu; Qingsong Liu; Ziping Qi; Beilei Wang; Aoli Wang; Xuesong Liu; Hefei Institutes of Physical Science; University of Science and Technology of China
Published: 2022-10-29T00:00:00+08:00

科学数据银行2022-11-01 更新2026-04-23 收录

激酶抑制剂开发

胃肠道间质瘤治疗

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资源简介：

Biochemical Kinase AssayMolecular ModelingAntiproliferation AssaysSignaling Pathway StudyApoptosis Effect ExaminationRodent Pharmacokinetics.Xenograft Model

提供机构：

Wenchao Wang; 合肥物质科学研究院; Qingwang Liu; Zongru Jiang; Zhenquan Hu; Fengming Zou; Junjie Wang; Kailin Yu; Qingsong Liu; Ziping Qi; Beilei Wang; Aoli Wang; Xuesong Liu; Hefei Institutes of Physical Science; University of Science and Technology of China

创建时间：

2022-10-29