B-cell epitopes (BCEs) are a set of specific sites on the surface of an antigen that binds to an antibody produced by B-cell. The recognition of BCEs is a major challenge for drug design and vaccines
Welcome to the official documentation for LBtope, an advanced computational tool designed to predict linear (continuous) B-cell epitopes from an antigen's primary sequence. Identifying these epitop
In this work, we developed a general perturbation theory and machine learning method for data mining of proteomes to discover new B-cell epitopes useful for vaccine design. The method predicts the epi
A total of 80 peptides with high antigenic scores, independently predicted from four different B-cell prediction algorithms, were selected for synthesis. AA: amino acid; AUC: area under the curve.
