We report high-throughput profiling of TRIM25 binding sites in triple negative breast cancer cells. ChIP-seq was performed using a TRIM25 antibody on 2 triple negative breast cancer cell lines
Given that LENG8 is associated with the THO complex and is required for mRNA processing, we went on to identify specific RNAs that bind LENG8 or THOC1. Therefore, we precipitated GFP-tagged THOC1, LEN
The development of triple-negative breast cancer (TNBC) is critically regulated by certain tumor-microenvironment-associated cells called mesenchymal stem/stromal cells (MSCs), which we and others hav
