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An autophagy CRISPR Screen in Jurkat cells

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NIAID Data Ecosystem2026-05-01 收录
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To identify genes regulating autophagy in human T-cells (Jurkat cell line) a CRISPR screen was conducted. Populations with low autophagic flux was sorted and the contained sgRNAs analysed by next-generation sequencing. Bioinformatic analysis compared the input of the screen versus the 'autophagy low' population. Comparison of sgRNA reads from input vs low autophagy population

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2023-10-11
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