During TCGA data analysis, we found that expression of many genes was correlated with the expression of MTDH in estrogen receptor (ESR) positive cancers. The effect of estradiol and MTDH on gene expre
As LRIG1 known to be a negative regulator of EGFR, we postulate that restored LRIG1 expression will change the transcription profile through the regulation of EGFR as well as its downstream signal cas
Compares shFOXO4 vs. Control in LNCaP grown in culture, or in nude mice as primary orthotopic tumors or lymph node metastases Overall design: RNA isolated from sub-confluent LNCaP (shFOXO4 vs. sh-Cont
For analysis of genes regulated by HP1γ in LUAD, we used microarray analysis to determine the global changes in gene expression upon HP1γ knockdown in H1792 cells and identified distinct sets of up-re