Crystal structure of TTK kinase domain in complex with compound 7
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Crystal structure of TTK kinase domain in complex with compound 7 Descriptor: 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Dual specificity protein kinase TTK Authors: Kim, H.L, Cho, H.Y, Park, Y.W, Lee, Y.H, Son, J.B, Ko, E.H, Choi, H.G, Kim, N.D. Deposit date: 2020-07-07 Release date: 2021-05-12 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor. J.Med.Chem., 64, 2021
创建时间：
2020-07-07
