Conversion of a Viral Glycan Shield into a Binding Anchor via Causal-Driven Antibody Optimization The Antibody Evolution Nexus with Causal-Driven Simulation (AENCS) is a white-box computational-exper
Effective biologic therapeutics require binding affinities that are fine-tuned to their disease-related molecular target. The ADAPT (Assisted Design of Antibody and Protein Therapeutics) platform aids
Therapeutic blockade of the CD47/SIRPα axis by small molecules or monoclonal antibodies (mAbs) is a proven strategy to enhance macrophages-mediated anti-tumor activity. However, this strategy has been
