Crystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in complex with pyrimethamine
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Crystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in complex with pyrimethamine Descriptor: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, Dihydrofolate reductase Authors: Dias, M.V.B, Tyrakis, P, Blundell, T.L. Deposit date: 2013-05-07 Release date: 2013-12-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs. Structure, 22, 2014
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2013-05-07
