Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 1.

Selective estrogen receptor downregulator antagonists: Tetrahydroisoquinoline phenols 1. Descriptor: (E)-3-[4-[(1R,3R)-6-hydroxy-2-isobutyl-3-methyl-3,4-dihydro-1H-isoquinolin-1-yl]phenyl]prop-2-enoic acid, ESTROGEN RECEPTOR ALPHA Authors: Scott, J.S, Bailey, A, Davies, R.D.M, Degorce, S.L, MacFaul, P.A, Gingell, H, Moss, T, Norman, R.A, Pink, J.H, Rabow, A.A, Roberts, B, Smith, P.D. Deposit date: 2015-12-14 Release date: 2016-02-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat. Acs Med.Chem.Lett., 7, 2016