Human NAMPT in complex with substrate NAM and small molecule activator NP-A1-S

Human NAMPT in complex with substrate NAM and small molecule activator NP-A1-S Descriptor: (3S)-1-[2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]-N-{[4-(methylsulfanyl)phenyl]methyl}piperidine-3-carboxamide, CHLORIDE ION, GLYCEROL, ... Authors: Ratia, K, Xiong, R, Shen, Z, Thatcher, G.R. Deposit date: 2022-07-22 Release date: 2023-03-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.429 Å) Cite: Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD. Biochemistry, 62, 2023