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Crystal structure of PDE4D complexed with a novel inhibitor

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Protein Data Bank Japan2024-03-27 更新2026-03-21 收录
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Crystal structure of PDE4D complexed with a novel inhibitor Descriptor: (1S)-6,7-dimethoxy-1-[2-(6-methyl-1H-indol-3-yl)ethyl]-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ... Authors: Zhang, X.L, Su, H.X, Xu, Y.C. Deposit date: 2018-10-24 Release date: 2019-10-23 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.872 Å) Cite: Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent. J.Med.Chem., 62, 2019

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2018-10-24
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