巨大芽孢杆菌L2液体发酵条件响应面优化数据集
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对试验结果进行多元二次回归分析,拟合模型形式为Y = β₀ + ΣβᵢXᵢ + ΣβᵢⱼXᵢXⱼ + ΣβᵢᵢXᵢ²,其中Xᵢ为因素编码值,β为回归系数;通过方差分析(ANOVA)评估模型及各因素的显著性,并计算决定系数R²与调整决定系数R²Adj评价模型拟合优度;利用拟合模型进行响应面分析,通过软件优化功能寻找使响应值Y最大化的因素水平组合(A, B, C),并计算预测值。
Multiple quadratic regression analysis was conducted on the experimental results, with the fitted model formulated as $Y = eta_0 + sumeta_i X_i + sumeta_{ij} X_i X_j + sumeta_{ii} X_i^2$, where $X_i$ represents the coded value of each factor and $eta$ denotes the regression coefficients. The significance of the overall model and individual factors was evaluated via Analysis of Variance (ANOVA), while the coefficient of determination ($R^2$) and adjusted coefficient of determination ($R^2_{Adj}$) were calculated to assess the model's goodness of fit. Response surface analysis was performed using the fitted model, and the software's optimization function was employed to find the factor level combination (A, B, C) that maximizes the response value Y, with the predicted value also calculated.




