RNA sequencing reveal impact of radiation on cardiac tissues

To study radiation-induced cardiac damage in mice, two groups of control and radiation mice were created, and cardiac tissues were obtained for bulk RNA sequencing. To explore the impact of radition on heart, mice were received 30 Gy 60Co γ-rays for irradiation. Subsequently, heart tissues were taken at 1 day and 6 weeks after irradiation for transcriptome sequencing. We performed bulk RNA sequencing to establish a comprehensive transcriptome profile of cardiac tissues under radiation.