Crystal structure of ABL1 in complex with CHMFL-074
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Crystal structure of ABL1 in complex with CHMFL-074 Descriptor: 1,2-ETHANEDIOL, 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]oxy}phenyl)-3-(trifluoromethyl)benzamide, CHLORIDE ION, ... Authors: Kong, L.L, Yun, C.H. Deposit date: 2016-01-27 Release date: 2016-07-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.529 Å) Cite: Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) Oncotarget, 7, 2016
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2016-01-27
