Remdesivir has displayed pharmacological activity against SARS-CoV-2. However, no pharmacometabolomics (PM) or correlation analysis with pharmacokinetics (PK) was revealed. Rats were intravenously adm
1. MX—S. pn group, JK—healthy group, TQ—ceftriaxone group, (QFY,QF)—QingFei Yin group 2. The file, MX,QF show the data that we extracted, VIP > 1 , p value ≤ 0.01 in red and p value ≤ 0.05 in
Note: A positive correlation coefficient indicates that higher concentrations of metabolites are associated with a better four-week response of depression status.Abbreviations: 5-MTPM = 5-methoxytrypt
Background: Chronic drug-induced liver injury (DILI) occurs in up to 20% of all DILI patients. It presents a chronic pattern with persistent or relapsed episodes and may even progress to cirrhosis. Ho