Highly parallel genome variant engineering with CRISPR/Cas9 S. cerevisiae

NIAID Data Ecosystem2026-05-17 收录

CRISPR/Cas9基因编辑

酵母基因功能研究

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https://www.ncbi.nlm.nih.gov/sra/SRP126350 数据链接链接失效反馈

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资源简介：

Examining the functional consequences of premature termination codons (PTCs) within yeast essential genes by targeted editing with CRISPR/Cas9

创建时间：

2017-12-20

Generation and sequence confirmation of an Odaph KO mouse model and a Slc13a5 KO mouse model

基因敲入小鼠模型

CRISPR/Cas9基因编辑

An _Odaph_^Cys41*^ mouse model homologous to human AI (p.Cys43*) was generated in C57BL/6J background using CRISPR/Cas9 and its exon and intron borders sequences were confirmed by Sanger sequencing. A

DataCite Commons2020-08-01 更新50

CIL:39679

细胞周期调控

酵母基因功能研究

10-hour timelapse of the double mutant Clb2dbΔ, Clb5Δ, which has the destruction box region of the CLB2 gene, on the cell cycle control system in budding yeast. The yeast, Saccharomyces cerevisia, are

Figshare2013-03-08 更新20

Table 5_Efficient GBA1 editing via HDR with ssODNs by outcompeting pseudogene-mediated gene conversion upon CRISPR/Cas9 cleavage.xlsx

CRISPR/Cas9基因编辑

同源定向修复

IntroductionCRISPR/Cas9-edited induced pluripotent stem cells (iPSCs) are valuable research models for mechanistic studies. However, gene conversion between a gene-pseudogene pair that share high sequ

NIAID Data Ecosystem10

Transcriptome analysis of conditional mutations in the genes encoding six different essential proteins that influence Sen1-dependent termination in Saccharomyces cerevisiae

转录终止机制

酵母基因功能研究

The information stored in the DNA of a cell’s chromosomes is transmitted to the rest of the cell by transcribing the DNA into RNA copies or “transcripts”. The fidelity of this process, and thus the he

NIAID Data Ecosystem40

Data_Sheet_1_The Codon Usage Bias Analysis of Free-Living Ciliates’ Macronuclear Genomes and Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Vector Construction of Stylonychia lemnae.DOCX

纤毛虫密码子偏性分析

CRISPR/Cas9基因编辑

Ciliates represent higher unicellular animals, and several species are also important model organisms for molecular biology research. Analyses of codon usage bias (CUB) of the macronuclear (MAC) genom

NIAID Data Ecosystem20

Highly parallel genome variant engineering with CRISPR/Cas9 S. cerevisiae

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