Enantioselective Coupling of Dienes and Phosphine Oxides
收藏NIAID Data Ecosystem2026-03-10 收录
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We report a Pd-catalyzed intermolecular hydrophosphinylation of 1,3-dienes to afford chiral allylic phosphine oxides. Commodity dienes and air stable phosphine oxides couple to generate organophosphorus building blocks with high enantio- and regiocontrol. This method constitutes the first asymmetric hydrophosphinylation of dienes.
创建时间：
2018-11-19
