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CRISPR-SURF analysis of tiling CRISPR screen data
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2020-07-10
相关数据集
Raw data_Supplementary figures.xlsx
Raw and minimal data set for the supplementary figures in paper titled Partial FAM19A5 deficiency in mice leads to disrupted spine maturation, hyperactivity, and an altered fear response.
DataCite Commons2025-06-11 更新210
Whole-genome CRISPR screen of etoposide-treated U2OS and U2OS p53KO cells, and RNAseq of U2OS cells incubated in media conditioned by etoposide-treated U2OS or U2OS p53KO cells.
CRISPR screen: U2OS or U2OS p53KO cells expressing Cas9 were transduced with a whole-genome library of CRISPR sgRNAs, then treated with either DMSO or etoposide. Differential sgRNA abundances were cal
NIAID Data Ecosystem00
Active growth signalling promotes senescence and cancer cell sensitivity to CDK7 inhibition. Active growth signalling promotes senescence and cancer cell sensitivity to CDK7 inhibition
Tumour growth is driven by continued cellular growth and proliferation. Cyclin Dependent Kinase 7’s (CDK7) role in activating mitotic CDKs and globalgene expression makes it therefore an attractive ta
NIAID Data Ecosystem00
Multiple tissue sequencing of WT and Scx-ko mice
We used RNA sequencing and a gene knockout mice model to reveal the critical functions of Scx in multiple tissues. Overall design: Multiple tissues of Wild type(WT) and Scx-/- limb cells derived from
NIAID Data Ecosystem20
The paired primers used for gene cloning, disruption, complement, silencing and expression.
*H = A, C or T; B = C, G or T; V = A, C or G; R = A or G. The enzyme sites are italicized while the gateway fragments for exchange are in bold.
Figshare2015-12-02 更新00
