Dataset related to article "Modifications to the framework regions eliminate chimeric antigen receptor tonic signaling"
收藏NIAID Data Ecosystem2026-03-13 收录
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Dataset of raw data related to article mentioned at title
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2022-03-22
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Data_Sheet_1_Arming Anti-EGFRvIII CAR-T With TGFβ Trap Improves Antitumor Efficacy in Glioma Mouse Models.PDF
Glioblastoma (GBM) is an aggressive malignancy with poor prognosis. New therapeutic strategies for GBM are urgently needed. Although clinical studies have demonstrated the feasibility and safety of ch
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mRNA profiling on CART19 produced from normal donors treated with vecabrutinib. mRNA profiling on CART19 produced from normal donors treated with vecabrutinib
RNA sequencing was performed on three biological replicates of 1) CART19 + vehicle, 2) CART19 + 1 uM vecabrutinib, 3) CART19 + 10 uM vecabrutinib. Overall design: T cells from normal donors were trans
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Additional file 7 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products
Additional file 7: Table S2. Differentially expressed genes in non-transduced and transduced CAR T-cell products.
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Gene expression profiles of CAR-T cells expressing constitutively active mutants of STAT3 and STAT5 [STAT3_3+5 _CART_rested]
Augmenting cytokine signaling represents a pivotal strategy to enhance the therapeutic efficacy of chimeric antigen receptor (CAR) T cell therapy. However, the distinct roles of the downstream transcr
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Additional file 2 of Hematologists’ barriers and enablers to screening and recruiting patients to a chimeric antigen receptor (CAR) T cell therapy trial: a theory-informed interview study
Additional file 2:. Physician belief statements.
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