Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme

Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SQUALENE--HOPENE CYCLASE, {4-[((1S,2S)-2-{[ALLYL(CYCLOPROPYL)AMINO]METHYL}CYCLOPROPYL)METHOXY]PHENYL}(4-BROMOPHENYL)METHANONE Authors: Lenhart, A, Reinert, D.J, Weihofen, W.A, Aebi, J.D, Dehmlow, H, Morand, O.H, Schulz, G.E. Deposit date: 2002-08-24 Release date: 2003-08-21 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene-Hopene Cyclase J.Med.Chem., 46, 2003