PRISMA Supplemental Figure 1 shows how records were identified and analyzed Supplemental Table 1 shows clinical background of patients included in analysis Supplemental Table 2 shows level of evidence
An R sript to calculate LD50s with 95% CLs, judge the significance between two LD50s, and measure parallelism of dose-response lines using probit-log(dose) model.
Values are means ± SD, #median and interquartile range for skewed variables, or %. Skewed variables were log-transformed prior to analysis. P-values for t-tests or *Fisher exact test are depicted and