ERα and AP-1 coordinate transcription and tamoxifen response in ERα-positive breast cancer
收藏NIAID Data Ecosystem2026-03-12 收录
官方服务：
资源简介：
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景：
创建时间：
2021-07-25
相关数据集
Estrogen-dependent gene expression in human breast cancer cells relies upon proteosome-dependent monoubiquitination of histone H2B
The estrogen receptor-alpha (ERα) determines breast cancer cell phenotype and is a prognostic indicator. A better understanding of the mechanisms controlling ERα function may uncover improved strategi
NIAID Data Ecosystem60
Myc activation in breast cancer is due to p53-loss and sustains self-renewal of cancer stem cells (ChIP-Seq). Mus musculus
Purpose: discover the downstream pathways and the mechanism of target activation by the p53:Myc axis in normal mammary and cancer stem cells Methods: we performed ChIPseq experiments from NMuMG cells
NIAID Data Ecosystem30
Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.
Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript
NIAID Data Ecosystem10
Idiosyncratic nature of lactation reveals link to breast cancer risk.
Breastfeeding protects against breast cancer in some women but not others, however the mechanism remains elusive. Lactation requires intense secretory activity of the endoplasmic reticulum (ER) for th
NIAID Data Ecosystem30
Unliganded Estrogen Receptor Beta cooperates with Argonaute 2 in the modulation of transcription rate and splicing of target genes in breast cancer cells. Part 1
Estrogen receptors (ERs) are primary targets for chemoprevention and endocrine therapy of breast cancer (BC) and provide prognostic and predictive information concerning tumor response to endocrine th
NIAID Data Ecosystem10
