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Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORgt

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORgt Descriptor: 5-(2,3-dichloro-4-{[(2S)-1,1,1-trifluoropropan-2-yl]sulfamoyl}phenyl)-4-(4-fluoropiperidine-1-carbonyl)-N-(2-hydroxy-2-methylpropyl)-1,3-thiazole-2-carboxamide, RAR-related orphan receptor C Authors: Spurlino, J, Milligan, C. Deposit date: 2020-02-12 Release date: 2020-05-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.202 Å) Cite: Optimization and biological evaluation of thiazole-bis-amide inverse agonists of ROR gamma t. Bioorg.Med.Chem.Lett., 30, 2020

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2020-02-12
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