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Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during root development

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NIAID Data Ecosystem2026-03-12 收录
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We show that Ror2 mediated non-canonical Wnt signaling in the dental mesenchyme plays a critical role in cell proliferation and thereby regulates root development size in mouse molars. Furthermore, Cdc42 acts as a potential downstream mediator of Ror2 signaling in root formation. Overall design: we detected the tooth development in in Ror2 conditional knockout mouse models

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2021-02-14
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