Functional similarity between asthma, eczema and rhinitis.

Numerical values show how similar is the use of a cellular pathway by pairs of trios of diseases. Similarity = 1 means that the diseases affect the pathway in exactly the same way. Similarity = 0 is represented by blank cells. Two asterisks: similarity is significantly larger than random expectation (z-test; P < 0.01). One asterisk: similarity is significantly larger than random expectation (z-test; P < 0.05). All significant similarities were also significantly larger than observed for pairs and trios of immune system diseases (empirical distribution test; P < 0.01).