Discovery of Highly Active Kynureninases for Cancer Immunotherapy through Protein Language Model

File Description Fig2_raw_data.xlsx: An Excel file containing raw data for Fig2. training_seqs.fasta: A fasta file used to train regression models. The number next to the accession is kcat/Km. nonredundant_target_sequences.fasta: A fasta file containing hits from MMseqs2 homology search of Pf-K protein against BFD and Metaclust2. The number next to the accession indicates the E-value. Top50_ranked_target_sequences.xlsx: An Excel file containing top50 sequences among hits from homology search, ranked by our protein language model based normalized random forest predictor.